This calculator is undergoing validation. Cross-check all calculations against primary sources or your institutional reference before clinical use.

Creatinine Clearance Calculator

Estimated renal function for adult drug dose adjustment. Includes Cockcroft-Gault and CKD-EPI 2021 equations.

Used by most drug package inserts for dose adjustment recommendations.

Patient

Age (years)

Sex

MaleFemale

Weight

Height

Serum creatinine

mg/dL

Body weight to use for dosing

Actual body weight (default)Ideal body weightAdjusted body weight (for obesity)

For obese patients (BMI ≥ 30), adjusted body weight is commonly preferred because actual weight overestimates CrCl. Ideal body weight may be more appropriate in some edge cases. Consult institutional protocols.

Enter age, sex, weight, height, and serum creatinine to see results.

References

Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16(1):31-41.

Inker LA, Eneanya ND, Coresh J, et al. New creatinine- and cystatin C-based equations to estimate GFR without race. N Engl J Med. 2021;385(19):1737-1749.

Levey AS, Coresh J, Greene T, et al. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med. 2006;145(4):247-254.

Devine BJ. Gentamicin therapy. Drug Intell Clin Pharm. 1974;8:650-655.

Mosteller RD. Simplified calculation of body-surface area. N Engl J Med. 1987;317(17):1098.

KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int. 2024;105(4S):S117-S314.

This calculator is intended for use by licensed pharmacy and healthcare professionals as an aid in estimating renal function for adult patients (≥18 years). It is not validated for pediatric patients, pregnancy, acute kidney injury, dialysis-dependent patients, or patients at extremes of muscle mass. Estimating equations approximate kidney function and may not reflect true GFR in any specific patient. Clinical judgment, trended labs, and direct measurement should guide drug dosing decisions when accuracy is critical.